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human t-cell leukemic cell line (cem)  (CEM Corporation)

 
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    CEM Corporation human t-cell leukemic cell line (cem)
    Human T Cell Leukemic Cell Line (Cem), supplied by CEM Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+t+cell+leukemic+cell+line%2C/cem+c1+cells/pm39073638-151-22-27
    Average 90 stars, based on 1 article reviews
    human t-cell leukemic cell line (cem) - by Bioz Stars, 2026-09
    90/100 stars

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    Cell Culture:

    Article Title: Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration
    Article Snippet: .. Human B cell leukemia cell line, Nalm6, and human T cell leukemic cell line, CEM were cultured in RPMI 1640 supplemented with 10% FBS and 100 U of penicillin G/mL and 100 mg/mL of streptomycin, as described before., − ..



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    Decarboxylation of F-5caC is a rapid process and occurs in diverse mammalian cells. (a–c) Quantification of F-5caC, F-dC, and F-5mC levels in genomic DNA of HEK293T cells upon feeding of 300 μM of F-5caC for different times. (d) Quantification of F-5caC, F-dC, and F-5mC levels in genomic DNA of Jurkat-T, MCF-7, and Neuro-2a cells upon feeding of 300 μM of F-5caC for 3 d. (e) Schematic illustration of the active 5mC demethylation through two pathways: the direct decarboxylation of TET-produced 5caC to cytosine in mammalian genomes established in the current study and the previous TET-TDG-BER pathway.

    Journal: Chemical Science

    Article Title: Direct decarboxylation of ten-eleven translocation-produced 5-carboxylcytosine in mammalian genomes forms a new mechanism for active DNA demethylation †

    doi: 10.1039/d1sc02161c

    Figure Lengend Snippet: Decarboxylation of F-5caC is a rapid process and occurs in diverse mammalian cells. (a–c) Quantification of F-5caC, F-dC, and F-5mC levels in genomic DNA of HEK293T cells upon feeding of 300 μM of F-5caC for different times. (d) Quantification of F-5caC, F-dC, and F-5mC levels in genomic DNA of Jurkat-T, MCF-7, and Neuro-2a cells upon feeding of 300 μM of F-5caC for 3 d. (e) Schematic illustration of the active 5mC demethylation through two pathways: the direct decarboxylation of TET-produced 5caC to cytosine in mammalian genomes established in the current study and the previous TET-TDG-BER pathway.

    Article Snippet: The human embryonic kidney epithelial cell line (HEK293T), human leukemic cell line (Jurkat-T), human breast adenocarcinoma cell line (MCF-7), and mouse neuroblastoma N2a cell line (Neuro-2a) were obtained from the China Center for Type Culture Collection (Wuhan, China).

    Techniques: Produced